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向慧静

  向慧静:女,博士后。 

  教育经历: 

  2011/09 – 2017/12,华东理工大学,化学与分子工程学院,无机化学专业,博士 

  科研工作简介: 

  纳米材料抗肿瘤治疗的研究 

  纳米药物可控释放及其生物学效应评价 

  纳米材料光致治疗的研究 

  主持的科研项目: 

  (1)    上海人才发展资金,2018114,肿瘤微环境响应的多功能介孔纳米光敏剂用于肿瘤光动力治疗研究,2018.11-2021.1130万元  

  (2)    中国博士后基金面上项目,2018M642097AIPH@Nb2C@mSiO2纳米体系的制备及其抗肿瘤活性研究,2018.11-2020.035万元 

  科研成果: 

  (1)    H. Xiang, H. Lin, L. Yu, Y. Chen, Hypoxia-Irrelevant Photonic Thermodynamic Cancer Nanomedicine. ACS Nano 2019, 13, 2223.  

  (2)    H. Xiang, Y. Chen, Energy-Converting Nanomedicine. Small 2019, DOI:10.1002/smll.201805339.  

  (3)    H. Xiang, F. Xue, T. Yi, H. P. Tham, J.-G. Liu, Y. Zhao, Cu2-xS Nanocrystals Cross-Linked with Chlorin e6-Functionalized Polyethylenimine for Synergistic Photodynamic and Photothermal Therapy of Cancer. ACS Appl. Mater. Interfaces 2018, 10, 16344-16351.  

  (4)    H. Xiang, H. Chen, H. P. Tham, S. Z. F. Phua, J.-G. Liu, Y. Zhao, Cyclometalated Iridium(III)-Complex-Based Micelles for Glutathione-Responsive Targeted Chemotherapy and Photodynamic Therapy. ACS Appl. Mater. Interfaces 2017, 9, 27553-27562.  

  (5)    H. Xiang, H. P. Tham, M. D. Nguyen, S. Z. F. Phua, W. Q. Lim, J.-G. Liu, Y. Zhao, Aza-BODIPY Based Near-Infrared Fluorescent Probe for Sensitive Discrimination of Cysteine/Homocysteine and Glutathione in Living Cells. Chem. Commun. 2017, 53, 5220-5223. 

  (6)    H. Xiang, Q. Deng, L. An, M. Guo, S.-P. Yang, J.-G. Liu, Tumor Cell Specific and Lysosome-Targeted Delivery of Nitric Oxide for Enhanced Photodynamic Therapy Triggered by 808 nm Near-Infrared Light. Chem. Commun. 2016, 52, 148-151.  

  (7)    H. Xiang, Min Guo, Lu An, Shi-Ping Yang, Qian-Ling Zhang and Jin-Gang Liu, A Multifunctional Nanoplatform for Lysosome Targeted Delivery of Nitric Oxide and Photothermal Therapy under 808 nm Near-Infrared Light. J. Mater. Chem. B 2016, 4, 4667-4674.  

  (8)    H. Xiang, L. An, W.-W. Tang, S.-P. Yang, J.-G. Liu, Photo-Controlled Targeted Intracellular Delivery of both Nitric Oxide and Singlet Oxygen Using a Fluorescence-Trackable Ruthenium Nitrosyl Functional Nanoplatform. Chem. Commun. 2015, 51, 2555-2558.  

  (9)    H. Xiang, M. Guo, J.-G. Liu, Transition-Metal Nitrosyls for Photo Controlled Nitric Oxide Delivery. Eur. J. Inorg. Chem. 2017, 2017, 1586-1595. 

  (10)   H. Xiang, J.-G. Liu, Y. Zhao, Recent Research Advancements in NO-Releasing Nanomaterials. Acta Phys. -Chim. Sin. 2017, 33, 903-917. 

  (11)   X.-D. Yang,+ H. Xiang,+ L. An, S.-P. Yang, J.-G. Liu, Targeted Delivery of Photoactive Diazido PtIV Complexes Conjugated with Fuorescent Carbon Dots. New J. Chem. 2015, 39, 800-804. (+ co-first author) 

  授权专利: 

  (1) 刘劲刚; 向慧静; 唐伟伟; 邓乔, 靶向性光控释放一氧化氮纳米复合材料药物体系及其制备方法, 2014.12.10-2034.06.20, 中国, CN201410280092.3 

  (2) 刘劲刚; 唐伟伟; 向慧静; 孙盼盼, 近红外光光控释放一氧化氮的纳米体系及其制法和应用, 2015.08.12-2035.03.31, 中国, CN201510149111.3 

  联系方式: 

  电话:021-52412058 

  邮箱:xianghuijing@mail.sic.ac.cn